Emergence of Drug-Resistant Influenza Virus: Population Dynamical Considerations

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Emergence of drug-resistant influenza virus: population dynamical considerations.

Given the considerable challenges to the rapid development of an effective vaccine against influenza, antiviral agents will play an important role as a first-line defense if a new pandemic occurs. The large-scale use of drugs for chemoprophylaxis and treatment will impose strong selection for the evolution of drug-resistant strains. The ensuing transmission of those strains could substantially ...

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ژورنال

عنوان ژورنال: Science

سال: 2006

ISSN: 0036-8075,1095-9203

DOI: 10.1126/science.1122947